Skip to content

Y-BLOKKA

Y-BLOKKA, 2019, sculpture, olive oil soap. The Y-Blokka sculpture was made of a long bar of imported olive oil soap during the ongoing conflict of removing the Y-Blokken at Akersgata 44, 0180 Oslo. The protest for the plan had great public momentum but no effect in saving the city planning changes to raze the building. The idea for the soap sculpture is the relationship to the Y form in the body and the impermanent qualities it has in both genetics and light. The bond between X and Y is dissolved in water, just as the soap will eventually become lesser and lesser when exposed to water. Yttrium and additional elemental qualities are connected to the Y-form. “The structure, the making and demolition, when brought into light with the human relationship with environment seemed evident to me, but wasn’t something people seemed willing to come to terms with. Perhaps only in the intimate moments of grief, do humans reflect on the memory of what their actions cause.” -Rachel W. Please visit this website for complete information: https://yblokka.no 

 

 

Referencing Y form in biology:

Definition
noun, plural: immunoglobulins
(1) Any of several classes of structurally related glycoproteins in the blood serum, produced by plasma cells as an immune response against foreign agents (antigens); antibody
(2) The fraction of the blood serum containing antibodies
Supplement
An immunoglobulin (Ig) is a glycoprotein; it is comprised of a glycan and a protein constituent. The basic functional unit of an immunoglobulin has a Y-shape. It consists of two identical heavy chains and two identical light chains. In each of these chains, there are variable and constant regions. The apical portion of the variable regions serves as antigen-binding site. The plasma cell produces immunoglobulins as a response to an antigen, i.e. non-self foreign agent.
The immunoglobulin may also be described in this way: it is composed of two Fab (fragment, antigen-binding) regions and one fc (fragment, crystallizable) region. The Fabs include the antigen-combining sites whereas the fc region consists of the remaining constant sequence domains of the heavy chains, cell-binding site, and complement-binding sites.
In placental mammals (including humans), there are five classes (or isotypes) of immunoglobulins based on structure and biological activity:

SS-B/La Antibodies, IgG, Serum

Reporting Name

SS-B/La Ab, IgG, S

Useful For

Evaluating patients with signs and symptoms of a connective tissue disease in whom the test for antinuclear antibodies is positive
Testing for SS-B/La antibodies is not useful in patients without demonstrable antinuclear antibodies.

Clinical Information

SS-B/La is an extractable nuclear antigen (ENA) composed of a 48-kD protein combined with RNA species. SS-B/La antibodies are found primarily in patients with Sjogren syndrome or lupus erythematosus (LE), where they occur with frequencies of approximately 60% and 15%, respectively.(1,2) SS-B/La antibodies occur only infrequently in the absence of SS-A/Ro antibodies.
SS-B/La is 1 of 4 autoantigens commonly referred to as extractable nuclear antigens (ENA). The other ENA are SS-A/Ro, RNP, and Sm (Smith). Each ENA is composed of 1 or more proteins associated with cytoplasmic or small nuclear RNA species (snRNA) ranging in size from 80 to 350 nucleotides. Antibodies to ENA are common in patients with connective tissue diseases (systemic rheumatic diseases) including LE, mixed connective tissue disease, Sjogren syndrome, scleroderma (systemic sclerosis), and polymyositis/dermatomyositis.
See Connective Tissue Disease Cascade (CTDC) in Special Instructions.

Interpretation

A positive result for SS-B/La antibodies is consistent with connective tissue disease, including Sjogren syndrome and lupus erythematosus.

Testing Algorithm

See Connective Tissue Disease Cascade (CTDC) in Special Instructions.

Report Available

1 to 3 days

Day(s) Performed

Monday through Saturday

Clinical Reference

1. Homburger H, Larsen S: Detection of specific antibodies. In Clinical Immunology: Principles and Practice. First edition. Edited by R Rich, T Fleisher, B Schwartz, et al. St. Louis, Mosby-Year Book, 1996, pp 2096-2109
2. Kotzin B, West S: Systemic lupus erythematosus. In Clinical Immunology Principles and Practice. Second edition. Edited by R Rich, T Fleisher, W Shearer, et al. St. Louis, Mosby-Year Book, 2001, pp 60.1-60.24

Method Name

Multiplex Flow Immunoassay

Specimen Type

Serum

Specimen Required

Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Specimen Volume: 0.5 mL

Specimen Minimum Volume

0.35 mL

Specimen Stability Information

Specimen Type
Temperature
Time
Special Container
Serum
Refrigerated (preferred)
21 days
Frozen
21 days

Special Instructions

Reference Values

<1.0 U (negative)
≥1.0 U (positive)
Reference values apply to all ages.

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer’s instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86235

LOINC Code Information

Test ID
Test Order Name
Order LOINC Value
SSB
SS-B/La Ab, IgG, S
33613-1
Result ID
Test Result Name
Result LOINC Value
SSB
SS-B/La Ab, IgG, S
33613-1
Mayo Clinic Laboratories | Neurology Catalog Additional Information:
mml-Behavioral, mml-Epilepsy, mml-Headache, mml-Movement-Disorders, mml-Demyelinating-Diseases, mml-Neuroimmunology, mml-Neuromuscular, mml-Autonomic, mml-Pediatric, mml-Spinal-Cord, mml-Neuro-ophthalmology

Share your thoughts

This site uses Akismet to reduce spam. Learn how your comment data is processed.

error: Contact artist for permissions.